Beta-2 Glycoprotein 1 (ß2GPI) Antibodies Report Format
Download Report Sample
Explore cutting-edge diagnostics. One click to preview your report sample.
What is the β2GPI Antibody Test?
The Beta-2 Glycoprotein 1 (β2GPI) antibody test detects autoantibodies directed against β2GPI, a protein involved in blood clotting. These antibodies are highly specific for Antiphospholipid Syndrome (APS) and are associated with thrombosis and pregnancy-related complications.
What is a β2GPI Antibodies Report Format?
A β2GPI report provides quantitative levels of IgG and/or IgM antibodies against β2GPI in the blood. It supports the diagnosis of APS when interpreted with clinical history and other laboratory findings.
Tests Included in β2GPI Antibodies Report
Test | Description |
β2GPI IgG/IgM | Measures the concentration of IgG and/or IgM antibodies against beta-2 glycoprotein 1. |
Key Parts of a β2GPI Antibodies Report
Key Part | Description |
Antibody Class | Specifies whether IgG or IgM was tested. |
Measured Value | Quantitative result expressed in standardized units (U/mL). |
Reference Range | Categorizes the result as negative, equivocal, or positive. |
Interpretation | Explains the relevance of the findings in clinical context. |
Normal Range for β2GPI Antibodies Report
Result | Value (U/mL) |
Negative | <20 |
Equivocal | 20–39 |
Positive | ≥40 |
Parameters to Consider in β2GPI Report
Parameter | Interpretation |
Isotype (IgG vs IgM) | IgG is more strongly associated with clinical complications. |
Persistent Positivity | Required (12 weeks apart) for APS diagnosis. |
Association with aCL | Presence of both increases the likelihood of thrombotic events. |
Clinical History | Important to correlate results with history of thrombosis or pregnancy loss. |
Guidelines for β2GPI Antibodies Report Format
Guideline | Description |
Unit Consistency | Report results in U/mL using validated lab standards. |
Confirmatory Testing | Repeat after 12 weeks to confirm persistence. |
Panel Integration | Often reported alongside aCL and lupus anticoagulant. |
What Do the Results Mean?
Result Type | Interpretation |
Negative | No significant β2GPI antibodies detected. |
Equivocal | May require retesting for clarity. |
Positive | Indicates increased risk for thrombosis or pregnancy complications—requires clinical follow-up. |
β2GPI Antibodies Report Interpretation
Test | Interpretation |
β2GPI IgG/IgM | Detects antiphospholipid antibodies specific to β2GPI, crucial for diagnosing Antiphospholipid Syndrome (APS). Persistent elevation confirms autoimmune risk. |
Effortless Lab Management Starts Here!
Experience the future of lab operations. One click to revolutionize your lab.
