Prostate Specific Antigen (PSA) Report Format

Pathology
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What is PSA?


Prostate Specific Antigen (PSA) is a protein produced by the prostate gland. PSA levels are measured to assess prostate health and are used to screen for prostate cancer, monitor treatment efficacy, or evaluate prostate conditions like benign prostatic hyperplasia (BPH).

Tests Included in PSA Report

Test

Description

Total PSA

Measures the total amount of PSA in the blood.

Free PSA

Measures the proportion of PSA that is unbound (free) in the blood.

PSA Ratio

Ratio of free PSA to total PSA; used to evaluate the risk of prostate cancer.

Key Parts of a PSA Report

Key Part

Description

Sample Type

Blood sample, typically taken from a vein (serum).

Test Method

Common method: Enzyme-Linked Immunosorbent Assay (ELISA).

Measured Value

Reported in ng/mL (nanograms per milliliter).

Reference Range

Varies based on age, sex, and lab standards.

Interpretation

Provides insights based on PSA levels, helping diagnose prostate conditions.

Normal Range for PSA Report

Test

Reference Range (Approximate)

Total PSA

< 4.0 ng/mL

Free PSA

> 25% of total PSA

PSA Ratio

Free PSA / Total PSA; a ratio of >25% suggests a lower risk of prostate cancer.

What Do the Results Mean?

Result Type

Interpretation

Normal PSA

Suggests no signs of prostate cancer or other prostate conditions.

Elevated PSA

May indicate prostate enlargement, infection, inflammation, or cancer.

Low Free PSA

Associated with a higher likelihood of prostate cancer.

High Free PSA

Suggests a lower risk of prostate cancer, commonly seen in benign prostate conditions.

Prostate Specific Antigen (PSA) Report Interpretation

Test

Interpretation

Total PSA

Elevated levels can indicate prostate cancer, BPH, or prostate inflammation/infection.

Free PSA

A lower ratio of free PSA to total PSA suggests a higher likelihood of prostate cancer.

PSA Ratio

A higher free-to-total PSA ratio typically suggests a benign prostate condition, while a lower ratio may indicate a malignancy.

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Structure of the DoraysLIS Report

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