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What is the objective of a Bilirubin Test?
Bilirubin is a naturally occuring substance that is formed as a result of the breakdown of red blood cells. Then, the red blood cells undergo transformation in the liver where it is turned into bile and subsequently vomited out of the body in the intestines. A Bilirubin Test can determine the amount of bilirubin in a person’s blood and help evaluate liver health as well as diseases like liver ailment, hemolysis, and bile duct obstruction.
3 different Blood Bilirubins can be classified as follows:
Total Bilirubin: This indicates the complete quantity of bilirubin present in blood, be it indirect or direct.
Direct Bilirubin or Conjugated Bilirubin: This is a type of bilirubin which is water soluble borne out of liver excretion in bile.
Indirect Bilirubin or Unconjugated Bilirubin: As Red blood cells are broken down, indirect bilirubin, which is soluble in fat emerges, This is transformed into direct bilirubin through the liver.
What is the format of a Bilirubin Total, Direct & Indirect report?
A Bilirubin Total, Direct, and Indirect Report displays the findings of a blood test conducted to evaluate the quantity of bilirubin in the blood. Such report will have many other parts however the following will be the most important:
Patient Information : Name, age, sex, medical history, and relevant symptoms.
Test Name : Bilirubin Total, Direct, and Indirect.
Test Results : The values for total, direct, and indirect bilirubin levels.
Reference Ranges : Normal levels for each form of bilirubin for comparison.
Interpretation : The physician’s analysis of the test results based on normal and abnormal ranges.
Remarks : Additional notes or recommendations for follow-up testing or treatment if necessary.
Tests Included in the Bilirubin Total, Direct & Indirect Report
Test
Description
Total Bilirubin
Measures the overall bilirubin level in the blood, including both direct and indirect bilirubin.
Direct Bilirubin (Conjugated)
Measures the water-soluble form of bilirubin that has been processed by the liver and excreted in bile.
Indirect Bilirubin (Unconjugated)
Measures the fat-soluble form of bilirubin, produced during the breakdown of red blood cells.
Key Parts of a Bilirubin Total, Direct & Indirect Report
Part
Description
Total Bilirubin
The total bilirubin level in the blood, which includes both direct and indirect forms.
Direct Bilirubin (Conjugated)
The fraction of bilirubin that has been processed by the liver and is water-soluble.
Indirect Bilirubin (Unconjugated)
The portion of bilirubin that has not yet been processed by the liver and is fat-soluble.
Test Results
Displays the actual test results for total, direct, and indirect bilirubin.
Reference Ranges
Normal levels of bilirubin for comparison to the patient's results.
Interpretation
The physician’s explanation of the results, indicating whether they are normal or abnormal.
Normal Ranges for Bilirubin Total, Direct & Indirect
Test Parameter
Normal Range
Total Bilirubin
0.1 to 1.2 mg/dL
Direct Bilirubin (Conjugated)
0.0 to 0.3 mg/dL
Indirect Bilirubin (Unconjugated)
0.1 to 0.8 mg/dL
Parameters to Consider in a Bilirubin Report
Parameter
Interpretation
Total Bilirubin
High Total Bilirubin : Can indicate liver disease, bile duct obstruction, or hemolysis. Normal Total Bilirubin : Indicates normal bilirubin processing by the liver.
Direct Bilirubin (Conjugated)
High Direct Bilirubin : Suggests liver disease, bile duct obstruction, or hepatitis. Normal Direct Bilirubin : Indicates proper processing and excretion of bilirubin.
Indirect Bilirubin (Unconjugated)
High Indirect Bilirubin : Indicates hemolysis, Gilbert's syndrome, or liver dysfunction. Normal Indirect Bilirubin : Indicates normal red blood cell breakdown and liver function.
Bilirubin Total, Direct & Indirect Report Format Guidelines
Include the patient’s details such as age, sex, and relevant medical history to provide context for the test results.
The results for total, direct, and indirect bilirubin should be clearly displayed, with normal reference ranges for comparison.
The interpretation should explain whether the bilirubin levels are normal, high, or low and suggest potential causes of abnormalities.
Additional remarks should include the potential need for follow-up testing, possible diagnoses, or changes in treatment.
Use tables to display the test results and reference ranges for clarity and easy comparison.
Include the physician's notes for further guidance on interpretation or next steps for treatment.
What Do the Results Imply?
The Bilirubin Total, Direct, and Indirect tests help assess the function of the liver, bile ducts, and red blood cell turnover. Here’s what the results may indicate:
High Total Bilirubin : Elevated levels of total bilirubin can suggest liver diseases such as hepatitis, cirrhosis, or gallstones, or hemolytic anemia (increased breakdown of red blood cells).
High Direct Bilirubin (Conjugated) : Increased levels may indicate issues with bile duct obstruction, hepatitis, or liver dysfunction, as the liver is unable to process and excrete bilirubin properly.
High Indirect Bilirubin (Unconjugated) : Elevated indirect bilirubin levels can indicate hemolysis, where red blood cells break down faster than the liver can process them, or a condition like Gilbert's syndrome, which affects bilirubin processing.
Normal Bilirubin Levels : Normal levels of total, direct, and indirect bilirubin suggest healthy liver function, normal red blood cell turnover, and proper bile secretion.
Download Bilirubin Total, Direct & Indirect Report Sample
You can download a Bilirubin Total, Direct, and Indirect Report Sample here to better understand the format and presentation of the results.
Bilirubin Total, Direct & Indirect Report Interpretation
Test
Interpretation
Total Bilirubin
High Total Bilirubin : Indicates liver disease, hemolysis, or bile duct obstruction. Normal Total Bilirubin : Healthy liver function and normal red blood cell breakdown.
Direct Bilirubin (Conjugated)
High Direct Bilirubin : Likely indicates liver issues, such as hepatitis or bile duct obstruction. Normal Direct Bilirubin : Normal liver processing and bile secretion.
Indirect Bilirubin (Unconjugated)
High Indirect Bilirubin : Suggests hemolysis, Gilbert's syndrome, or liver dysfunction. Normal Indirect Bilirubin : Indicates normal breakdown of red blood cells.
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FAQ’s
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