Coagulation Profile Report Format
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What is a Coagulation Profile?
A coagulation profile tests the blood's ability to clot. It measures various clotting factors and proteins involved in the coagulation process. This test is used to assess bleeding or clotting disorders and monitor anticoagulant therapy.
Tests Included in Coagulation Profile Report
Test | Description |
PT (Prothrombin Time) | Measures the time it takes for blood to clot. |
INR (International Normalized Ratio) | Standardizes PT to assess clotting ability. |
aPTT (Activated Partial Thromboplastin Time) | Measures the clotting time of blood when exposed to certain chemicals. |
Fibrinogen | Measures the level of fibrinogen, a protein essential for blood clot formation. |
D-dimer | Tests for fibrin degradation products; elevated in clotting disorders. |
Key Parts of a Coagulation Profile Report
Key Part | Description |
Sample Type | Blood sample, typically from a vein (plasma). |
Test Method | Common methods include PT, aPTT, and enzyme-linked immunosorbent assay (ELISA). |
Measured Value | Reported in seconds for PT, aPTT, and fibrinogen, and in ng/mL for D-dimer. |
Reference Range | Varies depending on the test and lab. |
Normal Range for Coagulation Profile
Test | Reference Range (Approximate) |
PT | 11 – 14 seconds |
INR | 0.8 – 1.2 |
aPTT | 25 – 35 seconds |
Fibrinogen | 200 – 400 mg/dL |
D-dimer | < 250 ng/mL |
What Do the Results Mean?
Result Type | Interpretation |
Normal | Indicates normal clotting function. |
Elevated PT/INR | May indicate liver disease, vitamin K deficiency, or use of blood thinners. |
Prolonged aPTT | Suggests bleeding disorders or use of anticoagulants. |
Low Fibrinogen | May indicate a clotting disorder, liver disease, or excessive clot breakdown. |
Elevated D-dimer | Suggests clot formation and breakdown; may indicate deep vein thrombosis (DVT), pulmonary embolism (PE), or disseminated intravascular coagulation (DIC). |
Coagulation Profile Report Interpretation
Test | Interpretation |
PT/INR | Evaluates overall clotting ability, often used to monitor blood thinner therapy. |
aPTT | Helps assess intrinsic clotting pathway and monitor anticoagulant therapy. |
Fibrinogen | Essential protein for clot formation; abnormal levels indicate clotting issues. |
D-dimer | Elevated in cases of abnormal clotting or clot breakdown. |
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