Coagulation Profile Report Format

Pathology
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What is a Coagulation Profile?


A coagulation profile tests the blood's ability to clot. It measures various clotting factors and proteins involved in the coagulation process. This test is used to assess bleeding or clotting disorders and monitor anticoagulant therapy.

Tests Included in Coagulation Profile Report

Test

Description

PT (Prothrombin Time)

Measures the time it takes for blood to clot.

INR (International Normalized Ratio)

Standardizes PT to assess clotting ability.

aPTT (Activated Partial Thromboplastin Time)

Measures the clotting time of blood when exposed to certain chemicals.

Fibrinogen

Measures the level of fibrinogen, a protein essential for blood clot formation.

D-dimer

Tests for fibrin degradation products; elevated in clotting disorders.

Key Parts of a Coagulation Profile Report

Key Part

Description

Sample Type

Blood sample, typically from a vein (plasma).

Test Method

Common methods include PT, aPTT, and enzyme-linked immunosorbent assay (ELISA).

Measured Value

Reported in seconds for PT, aPTT, and fibrinogen, and in ng/mL for D-dimer.

Reference Range

Varies depending on the test and lab.

Normal Range for Coagulation Profile

Test

Reference Range (Approximate)

PT

11 – 14 seconds

INR

0.8 – 1.2

aPTT

25 – 35 seconds

Fibrinogen

200 – 400 mg/dL

D-dimer

< 250 ng/mL

What Do the Results Mean?

Result Type

Interpretation

Normal

Indicates normal clotting function.

Elevated PT/INR

May indicate liver disease, vitamin K deficiency, or use of blood thinners.

Prolonged aPTT

Suggests bleeding disorders or use of anticoagulants.

Low Fibrinogen

May indicate a clotting disorder, liver disease, or excessive clot breakdown.

Elevated D-dimer

Suggests clot formation and breakdown; may indicate deep vein thrombosis (DVT), pulmonary embolism (PE), or disseminated intravascular coagulation (DIC).

Coagulation Profile Report Interpretation

Test

Interpretation

PT/INR

Evaluates overall clotting ability, often used to monitor blood thinner therapy.

aPTT

Helps assess intrinsic clotting pathway and monitor anticoagulant therapy.

Fibrinogen

Essential protein for clot formation; abnormal levels indicate clotting issues.

D-dimer

Elevated in cases of abnormal clotting or clot breakdown.

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Structure of the DoraysLIS Report

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