Malaria Antigen Report Format
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What is the Malaria Antigen Test?
The Malaria Antigen test is a rapid diagnostic test (RDT) that detects specific proteins (antigens) released by Plasmodium parasites in the blood. It helps in the quick diagnosis of malaria, particularly Plasmodium falciparum and Plasmodium vivax.
What is a Malaria Antigen Report Format?
A malaria antigen report presents the result of a rapid immunochromatographic test or ELISA, confirming the presence or absence of malarial infection. It may also differentiate between species, especially in dual antigen kits.
Tests Included in Malaria Antigen Report
Test | Description |
HRP2 (P. falciparum) | Detects Histidine-Rich Protein 2 antigen specific to P. falciparum. |
pLDH (Pan or Pv) | Detects parasite lactate dehydrogenase; Pan detects all species, Pv targets P. vivax. |
Key Parts of a Malaria Antigen Report
Key Part | Description |
Sample Type | Whole blood or EDTA blood. |
Test Method | Immunochromatographic card test (Rapid Test) or ELISA. |
Result | Reported as Positive, Negative, or Invalid for each antigen type. |
Interpretation | Indicates active infection and the species involved. |
Reference Range for Malaria Antigen Report
Antigen | Result |
HRP2 (Pf) | Negative: No P. falciparum antigen detected |
pLDH (Pan/Pv) | Negative: No malaria parasite antigen detected |
Parameters to Consider in Malaria Antigen Report
Parameter | Interpretation |
HRP2 Positive | Confirms infection with P. falciparum. |
pLDH Positive (Pan) | Indicates malaria infection; species identification may require microscopy. |
pLDH Positive (Pv) | Confirms infection with P. vivax. |
Dual Positivity | May suggest mixed infection—requires further confirmation. |
Guidelines for Malaria Antigen Report Format
Guideline | Description |
Test Timing | Most reliable during symptomatic febrile phase. |
Sample Handling | Ensure proper blood collection and timely testing. |
Species Differentiation | Report species if the kit supports it. Use microscopy or PCR if needed. |
What Do the Results Mean?
Result Type | Interpretation |
HRP2 Positive | Indicates active P. falciparum infection. |
pLDH Pan Positive | Suggests malaria infection—species not differentiated. |
pLDH Pv Positive | Indicates P. vivax infection. |
All Negative | No malaria antigen detected; infection unlikely or below detection limit. |
Malaria Antigen Report Interpretation
Test | Interpretation |
HRP2 / pLDH | Confirms presence of malaria antigen; differentiates between P. falciparum, P. vivax, or mixed infections. Best used for rapid screening in febrile patients. |
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