A kidney function test (KFT) is defined as blood and urine examinations done to assess the functioning capacity of the kidney. KFT evaluates the concentration of particular substances that the kidneys filter or synthesize, such as creatinine, urea, and other electrolytic constituents. KFT is an imperative test for ascertaining the existence of kidney sickness and for tracking the health of the kidney region, besides assessing the filtering capacity of the kidney vis a vis waste matter elimination.
A KFT report evaluates the kidney’s health by quantifying clinical parameters in blood and urine, hence producing the report. The KFT report analyzes the concentration of substances that are either synthesized or excreted by the kidney. The report helps in diagnosing renal dysfunction, estimating magnitudes of lesions, and supervising the course of treatment in cases of kidney pathology.
The tests get done after a patient presents symptoms suggestive of the kidney such as edema, tiredness, elevated blood pressure, or increased or decreased urine production and changes in routine tests among others. It is also advised during annual medical checkups for potential patients of kidney disorders like diabetics and hypertensive patients.
Test | Description |
Serum Creatinine | A waste product from muscle metabolism filtered by the kidneys. Elevated levels indicate poor kidney function. |
Blood Urea Nitrogen (BUN) | Measures the amount of nitrogen in the blood that comes from urea, a waste product produced in the liver and filtered by the kidneys. High levels can indicate kidney problems. |
Estimated Glomerular Filtration Rate (eGFR) | A calculation based on serum creatinine, age, gender, and ethnicity to estimate kidney function. Lower values suggest impaired kidney function. |
Urine Protein | Tests for protein levels in urine, which should normally be low. Elevated levels may indicate kidney damage. |
Urine Albumin-to-Creatinine Ratio (ACR) | An indicator of kidney damage, specifically in early kidney disease. |
Sodium (Na) | Measures sodium levels in the blood. Abnormal levels can indicate kidney issues or electrolyte imbalance. |
Potassium (K) | Measures potassium levels, which are regulated by the kidneys. High or low levels may suggest kidney dysfunction. |
Chloride (Cl) | Helps evaluate the kidney’s ability to maintain electrolyte balance. |
Bicarbonate (HCO3) | Measures the buffering capacity of blood, which kidneys regulate. Abnormal values can indicate kidney dysfunction. |
Test | Normal Range |
Serum Creatinine | 0.6 - 1.2 mg/dL |
Blood Urea Nitrogen (BUN) | 7 - 20 mg/dL |
eGFR | 90 - 120 mL/min/1.73m² |
Urine Protein | < 30 mg/g |
Urine ACR | < 30 mg/g |
Sodium (Na) | 135 - 145 mmol/L |
Potassium (K) | 3.5 - 5.0 mmol/L |
Chloride (Cl) | 98 - 106 mmol/L |
Bicarbonate (HCO3) | 22 - 28 mmol/L |
Parameter | Interpretation |
Serum Creatinine | Elevated creatinine suggests impaired kidney function, often seen in chronic kidney disease or acute kidney injury. |
BUN | Elevated BUN can suggest dehydration, kidney disease, or high-protein intake. Low levels may suggest malnutrition or liver disease. |
eGFR | A value < 60 mL/min/1.73m² for more than 3 months indicates chronic kidney disease. A value < 15 mL/min/1.73m² may require dialysis. |
Urine Protein | Increased protein in urine may suggest early kidney damage or disease. Persistent proteinuria is a key sign of kidney dysfunction. |
Urine ACR | A high ACR indicates kidney damage, particularly in diabetes and hypertension. |
Sodium | Low sodium can be caused by kidney disease or excessive fluid loss. High sodium may be a result of dehydration or kidney dysfunction. |
Potassium | Elevated potassium levels can be life-threatening and are commonly seen in kidney failure due to poor potassium excretion. |
Chloride | Abnormal chloride levels may indicate dehydration, kidney disease, or electrolyte imbalance. |
Bicarbonate | A low bicarbonate level suggests metabolic acidosis, which can result from chronic kidney disease. |
KFT results are crucial for diagnosing and monitoring kidney diseases, such as chronic kidney disease, glomerulonephritis, and acute kidney injury.
Test | Interpretation |
Serum Creatinine | Elevated creatinine indicates kidney dysfunction, commonly seen in chronic kidney disease or acute kidney injury. |
BUN | High BUN suggests kidney disease, dehydration, or high-protein intake. |
eGFR | A low eGFR suggests reduced kidney function, and values below 60 mL/min for more than 3 months are indicative of chronic kidney disease. |
Urine Protein | Protein in urine suggests early kidney damage or disease. |
Urine ACR | A high ACR indicates kidney damage, often seen in diabetic nephropathy or hypertension. |
Sodium | Abnormal sodium levels suggest dehydration, kidney dysfunction, or electrolyte imbalance. |
Potassium | High potassium levels may suggest kidney failure or impaired kidney function. |
Chloride | Abnormal chloride levels can be associated with dehydration, kidney dysfunction, or electrolyte imbalances. |
Bicarbonate | Low bicarbonate levels suggest metabolic acidosis, commonly seen in chronic kidney disease. |
This format provides a structured approach to KFT reports, offering clear interpretations and detailed explanations for each test result. Let me know if you need further refinement!
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